LDL “bad” cholesterol builds up in arteries and forms a sticky goo called plaque . Over time, plaque hardens blood vessels, making them so rigid that less blood can flow through them. This is called atherosclerosis.
Low density lipoprotein (LDL) particles are the major cholesterol carriers in circulation and their physiological function is to carry cholesterol to the cells. In the process of atherogenesis these particles are modified and they accumulate in the arterial wall.
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