NS1 tests detect the non-structural protein NS1 of dengue virus. This protein is secreted into the blood during dengue infection. NS1 tests have been developed for use in serum. Most of these tests use synthetically labeled antibodies to detect dengue NS1 protein.
A positive NS1 test result confirms dengue virus infection without providing serotype information. A negative NS1 test result does not rule out infection. People with negative NS1 results should be tested for the presence of dengue IgM antibodies to determine possible recent dengue exposure.
The most common symptom of dengue is fever with any of the following:
- Nausea, vomiting.
- Rash.
- Aches and pains (eye pain, typically behind the eyes, muscle, joint, or bone pain)
- Any warning sign.
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